Evidence Explorer

PubMed + Knowledge Graph · 4,421 papers · 55,850 graph nodes · 61M+ relationships

CollectionsResearch Feed
Knowledge Graph:200,000 nodes·61M+ relationships
Hybrid query:121ms avg
Dual-lane architecture:Proven + Experimental

Evidence Hierarchy (Oxford CEBM)

RCT (L6)PMID: 38291045IF: 176.1

Long-term outcomes of CRISPR-edited hematopoietic stem cells in sickle cell disease

Chen A, et al. · N Engl J Med · 2026

342 citationsn=1,200Relevance: 98%
Meta-Analysis (L7)PMID: 37856234IF: 168.9

Meta-analysis of CRISPR gene therapy trials for hemoglobinopathies

Williams R, et al. · Lancet · 2025

567 citationsn=4,500Relevance: 96%
Cohort Study (L5)PMID: 37123456IF: 25.4

BCL11A enhancer disruption restores fetal hemoglobin in adult erythroid cells

Park S, et al. · Blood · 2025

189 citationsn=340Relevance: 91%

How We Score Confidence

Evidence Factors

  • Study type hierarchy (Oxford CEBM levels)
  • Sample size and statistical power
  • Replication count across independent labs
  • Journal impact factor and peer review status

Graph Integration

  • Cross-references across 200K knowledge graph nodes
  • 61M+ relationship traversals for evidence chains
  • Hybrid queries (Supabase + Neo4j + Vector) in 121ms
  • Real-time PubMed sync with 24h update cycle